A Penetrating Look at Stochasticity in Development
نویسندگان
چکیده
In recent work published in Nature, Raj et al. (2010) use single mRNA molecule quantification to show that variation in gene expression in Caenorhabditis elegans increases in mutants displaying incomplete penetrance. They find that a bimodal response is triggered when noisy expression of an upstream regulator crosses a critical threshold.
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ورودعنوان ژورنال:
- Cell
دوره 140 شماره
صفحات -
تاریخ انتشار 2010